Nadia Moidu made her debut in a Malayalam movie named Nokketha Doorathu Kannum Nattu, along side Mohanlal and Padmini. This movie was re-made in Tamil as Poove Poochudava during the 1980s with Padmini and marked her debut in Tamil. She currently acts in leading character roles. She has acted alongside most of the leading artists in the Tamil and Malayalam film industries.
After marriage, Nadhiya Moidu settled abroad with her husband and two children. She currently resides in Mumbai with her family. She made a comeback with blockbuster hit M. Kumaran Son Of Mahalakshmi. The film received critical acclaim for her performance as Jeyam Ravi's mother. In 2008, she signed on as the brand ambassador for Arokya Milk and Thangamayil Jewellery. She recently appeared in a Tamil movie named Pattalam, which released on March 27, 2009. Nadhia currently hosts a popular television show called Jackpot, replacing actress Khusboo on Jaya TV.
One of her erstwhile childhood friends is actress Ponni Swaminathan of Bicycle Bride and Night of Henna fame.